![]() ![]() The isolated compound, 7,3',5'‑trimethoxyflavonol, was collected in yellow powder form was shown to be a flavonoids and was comprised of 18 carbon atoms and 16 hydrogen atoms. The animals were divided into four groups: K0, negative control K1, positive control K2, ethanol extract treated group and K3, ethyl acetate fraction treated group, and the lipid profiles were examined at the end of the study. ![]() An in vivo lipid‑lowering test used a randomized post‑test only control group experimental design in rats with hypercholesterolemia. The molecular structure of the isolated compound was determined using 1H‑nuclear magnetic resonance (NMR) and 13C‑NMR spectroscopy. The flavonoid compound was isolated using a maceration method, followed by gravity column chromatography until a pure compound was obtained. The present study aimed to isolate and identify flavonoid compounds from cogon grass roots and examine their potential as hypocholesterolemic agents. Cogon grass ( Imperata cylindrica/I. cylindrica) of the Gramineae family is found abundantly in nature, and the roots of this plant possess several beneficial biological properties.
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